Evaluation of a urine cortisol:creatinine ratio as a screening test for hyperadrenocorticism in dogs.

@article{Smiley1993EvaluationOA,
  title={Evaluation of a urine cortisol:creatinine ratio as a screening test for hyperadrenocorticism in dogs.},
  author={Lydia Smiley and Mark E Peterson},
  journal={Journal of veterinary internal medicine},
  year={1993},
  volume={7 3},
  pages={163-8}
}
The authors collected urine specimens in 31 normal dogs, 25 dogs with hyperadrenocorticism, 21 dogs in which hyperadrenocorticism was suspected but was not present, and 28 dogs with a variety of severe, nonadrenal diseases. Cortisol and creatinine were measured in unextracted urine by radioimmunoassay and spectrophotometry, respectively, and the cortisol:creatinine ratio was calculated for each specimen. The mean +/- SD urine cortisol:creatinine concentration ratio in the dogs with… CONTINUE READING

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