Evaluation of a triple combination of cytokeratin 20, p53 and CD44 for improving detection of urothelial carcinoma in urine cytology specimens

@inproceedings{Arville2013EvaluationOA,
  title={Evaluation of a triple combination of cytokeratin 20, p53 and CD44 for improving detection of urothelial carcinoma in urine cytology specimens},
  author={Brent Arville and Emily O’Rourke and F. W. Chung and Mahul B. Amin and Shikha Bose},
  booktitle={CytoJournal},
  year={2013}
}
BACKGROUND Atypical urine cytology results trigger cystoscopy or molecular tests, both of which are costly, complex and difficult to perform tests. Several immunostains are being investigated to improve cancer detection; however, cytology material is limited and restricts the use of multiple immunostains. This study was designed to determine the utility of a cocktail of three stains, cytokeratin (CK20), p53 and CD44 in urine cytology samples for improving the detection of urothelial carcinoma… CONTINUE READING
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