Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice.

@article{Rhodes2005EvaluationOA,
  title={Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice.},
  author={Justin S Rhodes and Karyn L Best and John K. Belknap and Deborah Ann Finn and J Christopher F Crabbe},
  journal={Physiology & behavior},
  year={2005},
  volume={84 1},
  pages={53-63}
}
Because of intrinsic differences between humans and mice, no single mouse model can represent all features of a complex human trait such as alcoholism. It is therefore necessary to develop partial models. One important feature is drinking to the point where blood ethanol concentration (BEC) reaches levels that have measurable affects on physiology and/or behavior (>1.0 mg ethanol/ml blood). Most models currently in use examine relative oral self-administration from a bottle containing alcohol… CONTINUE READING
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