Evaluation of a rapid immunochromatographic ODK0501 assay for detecting Streptococcus pneumoniae antigen in sputum samples from patients with lower respiratory tract infection.

@article{Izumikawa2009EvaluationOA,
  title={Evaluation of a rapid immunochromatographic ODK0501 assay for detecting Streptococcus pneumoniae antigen in sputum samples from patients with lower respiratory tract infection.},
  author={Koichi Izumikawa and Suguru Akamatsu and Akiko Kageyama and Kiyomi Okada and Yukumasa Kazuyama and Noboru Takayanagi and Shigeki Nakamura and Yuichi Inoue and Yasuhito Higashiyama and Kiyoyasu Fukushima and Tadashi Ishida and Toyomitsu Sawai and Kunihiko Yoshimura and Chikara Nakahama and Mitsuhide Ohmichi and Tomoyuki Kakugawa and Yasuhiko Nishioka and Nobuki Aoki and Masafumi Seki and Hiroshi Kakeya and Yoshihiro Yamamoto and Katsunori Yanagihara and Shigeru Kohno},
  journal={Clinical and vaccine immunology : CVI},
  year={2009},
  volume={16 5},
  pages={672-8}
}
A novel, rapid, and noninvasive test (ODK0501) to detect Streptococcus pneumoniae antigen was evaluated in a Japanese multicenter study. ODK0501 uses polyclonal antibodies to detect C polysaccharide of S. pneumoniae from sputum samples by an immunochromatographic assay. The utility of ODK0501 was evaluated for 161 adult patients with lower respiratory tract infection between March 2006 and March 2007. Bacterial culture and identification, real-time PCR, and ODK0501 assays were performed on… CONTINUE READING