Evaluation of a rapid and completely automated real-time reverse transcriptase PCR assay for diagnosis of enteroviral meningitis.

@article{Nolte2011EvaluationOA,
  title={Evaluation of a rapid and completely automated real-time reverse transcriptase PCR assay for diagnosis of enteroviral meningitis.},
  author={Frederick S Nolte and Beverly Barton Rogers and Yi-Wei Tang and Max Oberste and Christine C Robinson and Karen S Kehl and Kenneth A Rand and Harley A. Rotbart and Jos{\'e} Rafael Romero and A C Nyquist and David H. Persing},
  journal={Journal of clinical microbiology},
  year={2011},
  volume={49 2},
  pages={528-33}
}
Nucleic acid amplification tests (NAATs) for enterovirus RNA in cerebrospinal fluid (CSF) have emerged as the new gold standard for diagnosis of enteroviral meningitis, and their use can improve the management and decrease the costs for caring for children with enteroviral meningitis. The Xpert EV assay (Cepheid, Sunnyvale, CA) is a rapid, fully automated real-time PCR test for the detection of enterovirus RNA that was approved by the U.S. Food and Drug Administration for in vitro diagnostic… CONTINUE READING