Evaluation of a possible role for the dopamine d and d receptors in the steroid-dependent suppression of luteinizing hormone secretion in the seasonally anoestrous ewe.

@article{Curlewis1991EvaluationOA,
  title={Evaluation of a possible role for the dopamine d and d receptors in the steroid-dependent suppression of luteinizing hormone secretion in the seasonally anoestrous ewe.},
  author={Jonathan D. Curlewis and A. M. Naylor and Alan McNeilly},
  journal={Journal of neuroendocrinology},
  year={1991},
  volume={3 4},
  pages={387-91}
}
Abstract This study was undertaken to determine whether dopaminergic suppression of pulsatile luteinizing hormone (LH) secretion during seasonal anoestrus in the ewe is mediated via the dopamine D(1) or D(2) receptor. This was tested by 1) assessing the response to dopamine D(1) and D(2) antagonists during seasonal anoestrus, and 2) determining the ability of D(1) and D(2) agonists to suppress pulsatile LH secretion during the breeding season. In seasonally anoestrous ewes the D(2) antagonist… CONTINUE READING