Evaluation of a porcine model to study in vivo platelet activation.

Abstract

INTRODUCTION In order to investigate if decompression sickness involves platelet activation an animal model was evaluated. MATERIALS AND METHODS Twenty-four thiopentone-midazolam-fentanyl-anaesthetized pigs in four groups received 5-min infusions of adenosine diphosphate (25 mg/kg) or platelet activating factor (0.4 microg/kg). Groups 1 and 2 (adenosine… (More)

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