Evaluation of a novel ultra-sensitive nanoparticle probe-based assay for ricin detection.


A gold nanoparticle (GNP) probe-based assay (GNPA) modified from the bio-barcode assay (BCA) was developed for ultrasensitive detection of ricin, a potential biothreat agent. In the GNPA, a chain of ricin was captured by a GNP probe coated with polyclonal antibodies and single-stranded signal DNA. A magnetic microparticle (MMP) probe coated with ricin A… (More)
DOI: 10.3109/1547691X.2013.847994