Evaluation of a new vasodilating beta-blocking agent, carvedilol, in exertional angina using holter monitoring.

@article{Kishida1990EvaluationOA,
  title={Evaluation of a new vasodilating beta-blocking agent, carvedilol, in exertional angina using holter monitoring.},
  author={Hiroshi Kishida and Tomoaki Saito and Nagaharu Fukuma and Noritake Hata and Takayuki Suzuki and Fumiko Ohtsu},
  journal={Japanese heart journal},
  year={1990},
  volume={31 4},
  pages={
          449-60
        }
}
Antianginal and antiischemic effects and clinical pharmacologic actions of carvedilol, a novel beta-blocking agent with a vasodilator action, were determined by Holter electrocardiographic monitoring in 13 patients with exertional angina. The patients were observed for 1 week prior to entry into the study, followed by 1 to 2 weeks of treatment with carvedilol. During the observation period the patients received one placebo tablet daily, and during the treatment period one 20 mg tablet of… CONTINUE READING