Evaluation of a hormone receptor-positive ovarian carcinoma subtype with a favourable prognosis by determination of progesterone receptor and oestrogen receptor 1 mRNA expression in formalin-fixed paraffin-embedded tissue.

@article{Sinn2011EvaluationOA,
  title={Evaluation of a hormone receptor-positive ovarian carcinoma subtype with a favourable prognosis by determination of progesterone receptor and oestrogen receptor 1 mRNA expression in formalin-fixed paraffin-embedded tissue.},
  author={Bruno Valentin Sinn and Silvia Darb-Esfahani and Ralph Markus Wirtz and Jan Budczies and Jalid Sehouli and Radoslav Chekerov and Manfred Dietel and Carsten Denkert},
  journal={Histopathology},
  year={2011},
  volume={59 5},
  pages={918-27}
}
AIMS In vitro and epidemiological studies indicate an essential role for progesterone in the aetiology and progression of ovarian carcinoma. The aim of this study was to examine the prognostic role of progesterone receptor (PR) protein and mRNA expression. METHODS AND RESULTS PR expression was examined by immunohistochemistry (n=143) and kinetic reverse transcription-polymerase chain reaction (RT-PCR) from formalin-fixed and paraffin-embedded tissue (n=55). PR mRNA and protein expression… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 23 references

Expressions of estrogen and progesterone receptors in epithelial ovarian cancer: a clinicopathologic study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society • 2009
View 1 Excerpt

Predictive markers in breast cancer

SJ Payne, RL Bowen, JL Jones, CA. Wells
Histopathology • 2008

Antiestrogen therapy is active in selected ovarian cancer cases: the use of letrozole in estrogen receptor-positive patients.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2007
View 1 Excerpt

Estrogen, Progesterone and Epithelial Ovarian Cancer

Reproductive biology and endocrinology : RB&E • 2003
View 1 Excerpt

Inhibitory effects of progesterone on plasma membrane fluidity and tumorigenic potential of ovarian epithelial cancer cells

AC McDonnel, EA Van Kirk, DD Isaak, WJ. Murdoch
Exp. Biol. Med. (Maywood) • 2003

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