Evaluation of a fiber optic immunosensor for quantitating cocaine in coca leaf extracts.

@article{Toppozada1997EvaluationOA,
  title={Evaluation of a fiber optic immunosensor for quantitating cocaine in coca leaf extracts.},
  author={A R Toppozada and Jefferson Wright and Amira T. Eldefrawi and Mohyee E. Eldefrawi and Emanuel L. Johnson and Stephen D. Emche and Charles S Helling},
  journal={Biosensors & bioelectronics},
  year={1997},
  volume={12 2},
  pages={113-24}
}
A fiber optic evanescent fluoroimmunosensor was used to rapidly detect and quantitate coca alkaloids as cocaine equivalents in leaf extracts of five Erythroxylum species. A monoclonal antibody (mAb) made against benzoylecgonine (BE), a major metabolite of cocaine, was immobilized covalently on quartz fibers and used as the biological sensing element in the… CONTINUE READING