Evaluation of a Recombinant Antigen Enzyme-Linked Immunosorbent Assay (ELISA) in the Diagnostics of Antinuclear Antibodies (ANA) in Children with Rheumatic Disorders


The reliability and accuracy of ELISAs for the detection of circulating ANA in children with rheumatic diseases has recently been questioned. In this study we evaluated an allegedly superior ELISA method using recombinant antigens in a paediatric population with various rheumatic conditions and compared it to a conventional Hep-2 IFA assay. Sera from 123… (More)
DOI: 10.1007/s10067-002-8269-4


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