Evaluation of a New Vancomycin Dosing Protocol in Morbidly Obese Patients.

@article{Kosmisky2015EvaluationOA,
  title={Evaluation of a New Vancomycin Dosing Protocol in Morbidly Obese Patients.},
  author={Desiree E Kosmisky and Carrie L. Griffiths and Megan A Templin and James H. Norton and Kelly E. Martin},
  journal={Hospital pharmacy},
  year={2015},
  volume={50 9},
  pages={789-97}
}
BACKGROUND Optimal dosing of vancomycin in morbidly obese patients (>100 kg and at least 140% of their ideal body weight) has not been determined. Conventional dosing strategies have led to the observation of supratherapeutic trough concentrations (>20 mcg/mL). OBJECTIVE To evaluate the effectiveness of a new vancomycin dosing protocol in morbidly obese patients in achieving therapeutic trough concentrations between 10 and 20 mcg/mL and to determine patient-specific factors influencing the… CONTINUE READING

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