Evaluation of Three Different Methods to Establish Animal Models of Acanthamoeba Keratitis

@inproceedings{Ren2010EvaluationOT,
  title={Evaluation of Three Different Methods to Establish Animal Models of Acanthamoeba Keratitis},
  author={Meiyu Ren and Xinyi Wu},
  booktitle={Yonsei medical journal},
  year={2010}
}
PURPOSE To produce animal models of Acanthamoeba keratitis and to evaluate the advantages and adaptation range of each of the three methods employed. MATERIALS AND METHODS Mice and Wistar rats in three groups of 15 rats and 15 mice each were used to establish the models. Right corneas in group A were scratched and challenged with Acanthamoeba. Those in group B were scratched and covered with contact lenses incubated with Acanthamoeba. Those in group C received an intrastromal injection of… CONTINUE READING
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