Evaluation of TNF superfamily molecules in multiple myeloma patients: correlation with biological and clinical features.

@article{Lemancewicz2013EvaluationOT,
  title={Evaluation of TNF superfamily molecules in multiple myeloma patients: correlation with biological and clinical features.},
  author={Dorota Lemancewicz and Lukasz Bolkun and Ewa Jablonska and Agnieszka Kulczyńska and Urszula Bolkun-Skornicka and Janusz Kloczko and Janusz B. Dzieciol},
  journal={Leukemia research},
  year={2013},
  volume={37 9},
  pages={1089-93}
}
B-cell activating factor (BAFF), a proliferation-inducing ligand (APRIL) and apoptosis inducing ligand (TRAIL) are members of the tumour necrosis factor (TNF) family. They are the main survival factors for immature, naive and activated B cells. We have analysed BAFF, APRIL and TRAIL serum concentrations in 52 patients with newly diagnosed IgG multiple myeloma and 20 healthy volunteers. The values were significantly higher in the studied patients and advanced diseases, decreasing after… CONTINUE READING
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