Evaluation of Shifted Excitation Raman Difference Spectroscopy and Comparison to Computational Background Correction Methods Applied to Biochemical Raman Spectra

@inproceedings{Cordero2017EvaluationOS,
  title={Evaluation of Shifted Excitation Raman Difference Spectroscopy and Comparison to Computational Background Correction Methods Applied to Biochemical Raman Spectra},
  author={Eliana Cordero and Florian Korinth and Clara Stiebing and Christoph Krafft and Iwan W. Schie and J{\"u}rgen Popp},
  booktitle={Sensors},
  year={2017}
}
Raman spectroscopy provides label-free biochemical information from tissue samples without complicated sample preparation. The clinical capability of Raman spectroscopy has been demonstrated in a wide range of in vitro and in vivo applications. However, a challenge for in vivo applications is the simultaneous excitation of auto-fluorescence in the majority of tissues of interest, such as liver, bladder, brain, and others. Raman bands are then superimposed on a fluorescence background, which can… CONTINUE READING

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