Evaluation of SCCVII tumor cell survival in clamped and non-clamped solid tumors exposed to carbon-ion beams in comparison to X-rays.

@article{Hirayama2013EvaluationOS,
  title={Evaluation of SCCVII tumor cell survival in clamped and non-clamped solid tumors exposed to carbon-ion beams in comparison to X-rays.},
  author={Ryoichi Hirayama and Akiko Uzawa and Nobuhiro Takase and Yoshitaka Matsumoto and Miho Noguchi and Kana Koda and Masakuni Ozaki and Kei Yamashita and Huizi Li and Yuki Kase and Naruhiro Matsufuji and Sachiko Koike and Shin-ichiro Masunaga and Koichi Ando and Ryuichi Okayasu and Yoshiya Furusawa},
  journal={Mutation research},
  year={2013},
  volume={756 1-2},
  pages={146-51}
}
The aim of this study was to measure the RBE (relative biological effectiveness) and OER (oxygen enhancement ratio) for survival of cells within implanted solid tumors following exposure to 290MeV/nucleon carbon-ion beams or X-rays. Squamous cell carcinoma cells (SCCVII) were transplanted into the right hind legs of syngeneic C3H male mice. Irradiation with either carbon-ion beams with a 6-cm spread-out Bragg peak (SOBP, at 46 and 80keV/μm) or X-rays was delivered to 5-mm or less diameter… CONTINUE READING
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