Evaluation of PPI-0903M (T91825), a novel cephalosporin: bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests.

@article{Jones2005EvaluationOP,
  title={Evaluation of PPI-0903M (T91825), a novel cephalosporin: bactericidal activity, effects of modifying in vitro testing parameters and optimization of disc diffusion tests.},
  author={Ronald N. Jones and Thomas R. Fritsche and Yigong Ge and Kon{\'e} Kaniga and H{\'e}lio S. Sader},
  journal={The Journal of antimicrobial chemotherapy},
  year={2005},
  volume={56 6},
  pages={1047-52}
}
OBJECTIVES To evaluate bactericidal activity of PPI-0903M and in vitro testing parameters for this compound. METHODS A total of 110 strains were tested to determine MIC and MBC values of PPI-0903M. MIC values were determined by reference broth microdilution whereas MBC was assessed by plating the broth from the MIC well and from those wells above the MIC for each organism onto appropriate drug-free growth media. Seventeen strains were tested by the kill-curve methodology to again evaluate the… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
17 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 17 extracted citations

Similar Papers

Loading similar papers…