Evaluation of Nitrate Reductase Assay for Rapid Detection of Drug Resistant Tuberculosis

  title={Evaluation of Nitrate Reductase Assay for Rapid Detection of Drug Resistant Tuberculosis},
  author={Ranjit Kumar Sah and Dwij Raj Bhatta and Gokarna Raj Ghimire and Jeevan Bahadur Sherchand},
Emergence of multidrug-resistant tuberculosis (MDR-TB) urgently demands for simple, rapid and inexpensive methods of its detection for the effective treatment of drug resistant tuberculosis, particularly in low-income countries. A total of 113 clinical isolates of M. tuberculosis were tested for four first line antitubercular drugs by nitrate reductase assay (NRA) and were compared with standard proportion method to evaluate NRA efficacy. Results were available in 7 14 days by NRA as compared… CONTINUE READING


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