Evaluation of NID2 promoter methylation for screening of Oral squamous cell carcinoma

  title={Evaluation of NID2 promoter methylation for screening of Oral squamous cell carcinoma},
  author={Ratakorn Srisuttee and Areeya Arayataweegool and Patnarin Mahattanasakul and Napadon Tangjaturonrasme and Virachai Kerekhanjanarong and Somboon Keelawat and Apiwat Mutirangura and Nakarin Kitkumthorn},
  journal={BMC Cancer},
Oral squamous cell carcinoma (OSCC) is an aggressive human malignancy. Because of late diagnosis and recurrence of OSCC, the treatment of patients with OSCC is often ineffective. Thus, finding novel biomarkers of OSCC are essential. Here we derived a methylation marker by utilizing methylation microarray data and testing its capacity in cross-sectional study designed for OSCC detection and screening. According to bioinformatics analysis of total of 27,578 cg sites, cg22881914 of Nidogen 2 (NID2… 
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