Evaluation of Macroalgae Sulfated Polysaccharides on the Leishmania (L.) amazonensis Promastigote

@article{Pires2013EvaluationOM,
  title={Evaluation of Macroalgae Sulfated Polysaccharides on the Leishmania (L.) amazonensis Promastigote},
  author={Camila Lehnhardt Pires and Selma Dzimidas Rodrigues and Daniel Bristot and Henrique Hessel Gaeta and Daniela de Oliveira Toyama and Wladimir Ronald Lobo Farias and Marcos Hikari Toyama},
  journal={Marine Drugs},
  year={2013},
  volume={11},
  pages={934 - 943}
}
The sulfated polysaccharides from Solieria filiformis (Sf), Botryocladia occidentalis (Bo), Caulerpa racemosa (Cr) and Gracilaria caudata (Gc) were extracted and extensively purified. These compounds were then subjected to in vitro assays to evaluate the inhibition of these polysaccharides on the growth of Leishmania (L.) amazonensis promastigotes. Under the same assay conditions, only three of the four sulfated polysaccharides were active against L. amazonensis, and the polysaccharide purified… Expand
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