Evaluation of MMP3 and TIMP1 as candidate genes for high myopia in young Taiwanese men.

@article{Liang2006EvaluationOM,
  title={Evaluation of MMP3 and TIMP1 as candidate genes for high myopia in young Taiwanese men.},
  author={C Liang and H S Wang and Kuo-Sheng Hung and Edward Hsi and Angel Sun and Yi-Hui Kuo and S. H. Juo},
  journal={American journal of ophthalmology},
  year={2006},
  volume={142 3},
  pages={518-20}
}
PURPOSE We studied the relationship between high myopia and the MMP3 and TIMP1 genes. DESIGN Case-control study. METHODS We enrolled 150 high myopic individuals (< or = -6 diopters) and 262 controls (> or = -1.5 diopters) initially, and another 216 cases and 474 controls were enrolled for genotyping promising polymorphisms for replication. Thirteen polymorphisms were genotyped in the initial data. Logistic regression was used to test for genetic effects. Subset analyses were performed… CONTINUE READING

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