Evaluation of Hepatoprotective Effects of Raphanas sativus L.

  title={Evaluation of Hepatoprotective Effects of Raphanas sativus L.},
  author={Rifat-uz-Zaman and Mobasher Ahmad},
  journal={Journal of Biological Sciences},
Study to investigate the pancreatic regeneration and evaluation of the antidiabetic and antihyperlipidemic potential of aerial parts of Allium cepa
The aim of this study was carried out to investigate, clarify the pancreatic regeneration, and recommend in different fractions of the ethanol extract Allium cepa (onion) L. Antidiabetic andExpand
Anticarcinogenic Effect of Raphanus Sativus on 1 , 2 Dimethylhydrazine ( DMH ) Induced Colon Cancer in Rats
It is shown that -galactan of Raphanus sativus has pronounced cytotoxic effects on colon cancer cell line and might be a suitable candidate as a chemopreventive and as an adjuvant therapy for colon cancer. Expand
Comparative hypoglycemic activity of different extracts of Teucrium stocksianum in diabetic rabbits
In the present study crude powder and various extracts of Teucrium stocksianum were evaluated for antidiabetic effect in alloxan-induced diabetic rabbits. Crude extract significantly reduced bloodExpand
Effect of Mercuric Chloride on Hepatic Phosphatases and Transaminases in Albino Rat
Mercuric chloride is a serious health hazard and produces various disorders. However, phosphatases and transaminases are marker enzymes of hepatic toxicity. Twenty four adult albino rats have takenExpand
Protective effect of leaves of Raphinus sativus Linn on experimentally induced gastric ulcers in rats.
The leaf extracts of R. sativus Linn are found to possess antiulcer property in the experimental animal models of gastric ulcers, which is consistent with the literature report in the folk medicine. Expand
Simultaneous determination of quercetin, rutin and kaempferol in the leaf extracts of Moringa oleifera Lam. and Raphinus sativus Linn. by liquid chromatography-tandem mass spectrometry.
The results indicate that the LC-MS/MS method is fast and sensitive and may provide excellent specificity for simultaneous determination of quercetin, rutin and KA in leaf extracts of M.oleifera and R.sativus. Expand
Mexican plants with hypoglycaemic effect used in the treatment of diabetes.
A review of species commonly used in México in the treatment of diabetes mellitus, highlighting the current knowledge about these botanicals, but also the enormous gaps in knowledge as it relates to the species' toxicology, the pharmacokinetics of its active constituents and their metabolism. Expand


Evidence for Prostaglandin-Producing Supressor Cells in HCV Patients with Normal ALT
The results suggest that prostaglandin-producing suppressor may play a role in chronic HCV infection by inhibiting cellular immune responses in patients with persistently normal ALT. Expand
Antioxidant constituents of radish sprout (Kaiware-daikon), Raphanus sativus L.
Several kinds of sinapinic acid esters and flavonoids were isolated with high radical scavenging potency, which must contribute substantially to the activity. Expand
Epirubicin in patients with liver dysfunction: development and evaluation of a novel dose modification scheme.
Epirubicin dosing based on AST is safe and may reduce pharmacokinetic variability, and adaptive dosing was evaluated prospectively in a third group of 41 women with serum AST > or =2xnormal+/-raised bilirubin. Expand
Inhibition by Terbutaline of Nitric Oxide and Superoxide Anion Levels of Endotoxin-Induced Organs Injury in the Anesthetized Rat
The findings suggest that the amelioration of circulatory failure and organs injury by terbutaline is associated with its suppression in TNF-&agr;, O2·− and NO (via iNOS) production in animals with endotoxic shock. Expand
Short-term depletion of catalase suppresses cadmium-elicited c-Jun N-terminal kinase activation and apoptosis: role of protein phosphatases.
It is reported thatCatalase is crucial for the activation of JNK by Cd and that short-term depletion of catalase activity may facilitate okadaic acid-sensitive PP to down-regulate the JNK activation and may predispose these cells to carcinogenic transformation upon Cd exposure. Expand
A novel role of alkaline phosphatase in protection from immunological liver injury in mice.
Evidence is provided that alkaline phosphatase may contribute to protection from injury by a mechanism involving neutralization of endotoxin, and Levamisole may make normal hepatocytes, like the hepatocytes from liver-injured mice, highly sensitive to lipopolysaccharide through inhibiting AP synthesis. Expand
Attenuated acute liver injury in mice by naked hepatocyte growth factor gene transfer into skeletal muscle with electroporation
In mice given the HGF gene, HGF in plasma was increased up to fourfold from pretreatment amounts, peaking 6–9 days after electroporation and quickly decreasing within three weeks, compared with the group without HGF transfer, which can attenuate acute liver injury. Expand
Effect of arsenic, cadmium and lead on the induction of apoptosis of normal human mononuclear cells
The results indicate that both arsenic and cadmium are able to induce apoptosis of lymphoid cells, and suggest that this phenomenon may contribute to their immunotoxic effect in vivo. Expand
Effects of black radish root (Raphanus sativus L. var niger) on the colon mucosa in rats fed a fat rich diet
After treatment with granules from black radish root all of the histopathological changes and parameters of the redox state caused by the fat‐rich diet were improved and no inflammation was observed. Expand