Evaluation of HIV testing algorithms in Ethiopia: the role of the tie-breaker algorithm and weakly reacting test lines in contributing to a high rate of false positive HIV diagnoses

@inproceedings{Shanks2015EvaluationOH,
  title={Evaluation of HIV testing algorithms in Ethiopia: the role of the tie-breaker algorithm and weakly reacting test lines in contributing to a high rate of false positive HIV diagnoses},
  author={Leslie Shanks and Mahwash Siddiqui and Jarmila Klie{\vs}{\vc}ikov{\'a} and Neil E Pearce and Cono A Ariti and Libsework Muluneh and Erwan Pirou and Koert Ritmeijer and Johnson Masiga and Almaz Abebe},
  booktitle={BMC infectious diseases},
  year={2015}
}
BACKGROUND In Ethiopia a tiebreaker algorithm using 3 rapid diagnostic tests (RDTs) in series is used to diagnose HIV. Discordant results between the first 2 RDTs are resolved by a third 'tiebreaker' RDT. Médecins Sans Frontières uses an alternate serial algorithm of 2 RDTs followed by a confirmation test for all double positive RDT results. The primary objective was to compare the performance of the tiebreaker algorithm with a serial algorithm, and to evaluate the addition of a confirmation… CONTINUE READING
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