Evaluation of Gnrh Contraceptive Vaccine Using Domestic Swine as a Model for Feral Hogs

@inproceedings{Rhyan2004EvaluationOG,
  title={Evaluation of Gnrh Contraceptive Vaccine Using Domestic Swine as a Model for Feral Hogs},
  author={Jack C. Rhyan and Gary J. Killian},
  year={2004}
}
We determined the effect of a GnRH vaccine on reproductive function of sexually mature 5-month female and male domestic swine. The vaccine, GonaCon, developed at NWRC contains a GnRH peptide conjugated to KLH, combined with AdjuVac adjuvant also developed at NWRC. Four groups of ten females were given single IM immunizations either of 800μg GnRH vaccine, 1600μg GnRH vaccine, a prime and boost of 400μg GnRH vaccine and a sham dose adjuvant alone (control). At 8 months old, females were evaluated… CONTINUE READING

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