Evaluation of Genetic Variations in Organic Cationic Transporter 3 in Depressed and Nondepressed Subjects

@inproceedings{Hengen2011EvaluationOG,
  title={Evaluation of Genetic Variations in Organic Cationic Transporter 3 in Depressed and Nondepressed Subjects},
  author={Nina Hengen and Mitsi H. Lizer and Robert Kidd},
  booktitle={ISRN pharmacology},
  year={2011}
}
Organic cationic transporter 3 (OCT3, SLS22A3) has only recently emerged as one of the regulators of monoaminergic neurotransmission, which plays a critical role in the pathogenesis of depression and is a potential new antidepressant drug target. OCT3 single-nucleotide polymorphisms (SNPs) have been investigated for their association with psychiatric disorders such as methamphetamine use disorder and obsessive-compulsive disorder in children and adolescents, but not depression. This study was… CONTINUE READING

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