• Materials Science
  • Published 2006

Evaluation of Fluoropolymer Frit Performance in High-pH Nano-ESI Applications

@inproceedings{Wynn2006EvaluationOF,
  title={Evaluation of Fluoropolymer Frit Performance in High-pH Nano-ESI Applications},
  author={Jeffrey Wynn and Adam W. Perala and Christopher J. Toher and Gary A. Valaskovic},
  year={2006}
}
Nanoelectrospray applications at high pH require emitters of superior robustness under alkaline conditions. Conventional methodology mandates frequent emitter and column replacement due to deterioration of silica via base-induced hydrolysis1. Columns with an integral fluoropolymer frit combine the advantages of optimum sensitivity, band-broadening elimination, and exceptional longevity with enhanced resistance to high-pH conditions. 

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