Evaluation of ERα and VDR gene polymorphisms in relation to bone mineral density in Turkish postmenopausal women

@article{Kurt2012EvaluationOE,
  title={Evaluation of ERα and VDR gene polymorphisms in relation to bone mineral density in Turkish postmenopausal women},
  author={Ozlem Kurt and Hulya Yilmaz-Aydogan and Mehmet Uyar and Turgay Isbir and Mehmet Fatih Seyhan and Ayse Can},
  journal={Molecular Biology Reports},
  year={2012},
  volume={39},
  pages={6723-6730}
}
It has been suggested that the estrogen receptor alpha (ERα) and vitamin D receptor (VDR) genes as possibly implicated in reduced bone mineral density (BMD) in osteoporosis. The present study investigated the relation of ERα PvuII/XbaI polymorphisms and VDR FokI/TaqI polymorphisms with BMD in Turkish postmenopausal women. Eighty-one osteoporotic and 122 osteopenic postmenopausal women were recruited. For detection of the polymorphisms, polymerase chain reaction-restriction fragment lenght… CONTINUE READING
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