Evaluation of Domperidone Dosages and Delivery Methods for the Treatment of Fescue Toxicosis in Beef Heifers 1

@inproceedings{Jones2008EvaluationOD,
  title={Evaluation of Domperidone Dosages and Delivery Methods for the Treatment of Fescue Toxicosis in Beef Heifers 1},
  author={Kimberly L. Jones and Joseph L Schulze and James R. Strickland and Dee L. Cross and Patrick James Burns and R. M. Gilley and Errol Bassoo and Kellen B. Hart and Donald L. Thompson and Sarah Sanderson King},
  year={2008}
}
The objective of this study was to develop a practical method of domperidone delivery to ameliorate fescue toxicosis. Experiment 1 used heifers assigned to 7 treatment groups (n = 6 each): positive control (0.44 mg domperidone/kg BW daily s.c. for 9 d), negative control, and 0.22, 0.44, 0.88, and 1.76 mg domperidone/kg BW per os daily for 9 d, or a 3 g domperidone i.m. injection. Blood was collected every third day for 24 d. Domperidone concentrations in the 0.88 and 1.76 mg/kg BW treatments… Expand