Evaluation of Crohn’s disease activity: Initial validation of a magnetic resonance enterography global score (MEGS) against faecal calprotectin

@article{Makanyanga2013EvaluationOC,
  title={Evaluation of Crohn’s disease activity: Initial validation of a magnetic resonance enterography global score (MEGS) against faecal calprotectin},
  author={Jesica C. Makanyanga and Doug Pends{\'e} and Nikolaos Dikaios and Stuart H Bloom and Sara McCartney and Emma Helbren and Elaine Atkins and Terry Cuthbertson and Shonit Punwani and Alastair Forbes and Steve Halligan and Stuart A. Taylor},
  journal={European Radiology},
  year={2013},
  volume={24},
  pages={277-287}
}
To develop an MRI enterography global score (MEGS) of Crohn’s disease (CD) activity compared with a reference standard of faecal calprotectin (fC), C-reactive protein (CRP) and Harvey-Bradshaw index (HBI). Calprotectin, CRP and HBI were prospectively recorded for 71 patients (median age 33, male 35) with known/suspected CD undergoing MRI enterography. Two observers in consensus scored activity for nine bowel segments, grading mural thickness, T2 signal, mesenteric oedema, T1 enhancement and… CONTINUE READING
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