Evaluation of Cancer Stem Cell Markers CD133, CD44, CD24: Association with AKT Isoforms and Radiation Resistance in Colon Cancer Cells

@inproceedings{Sahlberg2014EvaluationOC,
  title={Evaluation of Cancer Stem Cell Markers CD133, CD44, CD24: Association with AKT Isoforms and Radiation Resistance in Colon Cancer Cells},
  author={Sara H{\"a}ggblad Sahlberg and Diana Spiegelberg and Bengt Glimelius and Bo Stenerl{\"o}w and Marika Nestor},
  booktitle={PloS one},
  year={2014}
}
The cell surface proteins CD133, CD24 and CD44 are putative markers for cancer stem cell populations in colon cancer, associated with aggressive cancer types and poor prognosis. It is important to understand how these markers may predict treatment outcomes, determined by factors such as radioresistance. The scope of this study was to assess the connection between EGFR, CD133, CD24, and CD44 (including isoforms) expression levels and radiation sensitivity, and furthermore analyze the influence… CONTINUE READING
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A subpopulation of CD24(+) cells in colon cancer cell lines possess stem cell characteristics

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