• Corpus ID: 30207544

Evaluation of Caffeine Gels on Physicochemical Characteristics and In Vivo Efficacy in Reducing Puffy Eyes

@inproceedings{Amnuaikit2011EvaluationOC,
  title={Evaluation of Caffeine Gels on Physicochemical Characteristics and In Vivo Efficacy in Reducing Puffy Eyes},
  author={Thanaporn Amnuaikit and Duangkhae Maneenuan and Prapaporn Boonme},
  year={2011}
}
The eyelids are the thinnest skin in the body, leading to be easy for the blood vessels to show through the skin caused a swollen and dark appearance called puffy eyes. Placing refrigerated damp tea bags on the eyelids has been believed for a long time that it can reduce the puffy eyes due to the vasoconstriction of caffeine. This study aimed to characterize physicochemical properties and to determine in vivo efficacy in reducing puffy eyes of the prepared caffeine gels. The formulation… 
japsonline.com
11 Citations
Background Citations
4

Figures from this paper

11 Citations

Citation Type

Citation Type

Caffeine’s Mechanisms of Action and Its Cosmetic Use
TLDR
Caffeine is being increasingly used in cosmetics due to its high biological activity and ability to penetrate the skin barrier and also stimulates the growth of hair through inhibition of the 5-α-reductase activity.
Effects of a cellulose mask synthesized by a bacterium on facial skin characteristics and user satisfaction
TLDR
The cellulose mask increased moisture levels in the skin significantly more than moist towels (P < 0.05) after a single application and user satisfaction with the product was evaluated.
Effective Home Remedies that Provide Quick Relief for Puffy Eyes
TLDR
Women find cold compression, cucumber, and getting enough sleep most effective in dealing with eye puffiness, while vitamin E, K, caffeine treatments and witch hazel were less popular.
Method developments approaches in supercritical fluid chromatography applied to the analysis of cosmetics.
Simultaneous Determination of Caffeine, Preservatives and Antioxidants in Energy- and Soft-Drinks Commercially Available in Bangladesh
This study describes a validated assay method to determine caffeine, benzoic acid, methylparaben, propylparaben, butylparaben, butylatedhydroxyanisole, and butylatedhydroxytoluene simultaneously by…
Effect of Drug Loading Method and Drug Physicochemical Properties on the Material and Drug Release Properties of Poly (Ethylene Oxide) Hydrogels for Transdermal Delivery
TLDR
The drug release mechanism for the majority of medicated PEO hydrogel formulations was determined as both drug diffusion and polymer chain relaxation, which is highly desirable for controlled release formulations.
Redirecting drug repositioning to discover innovative cosmeceuticals
TLDR
“target repositioning” is proposed, a new term, to highlight that druggable protein targets implicated in multiple diseases can be exploited to accelerate the discovery of molecularly targeted cosmeceuticals that can promote skin health as an added benefit, which is a novel concept not described before.
Infraorbital Dark Circles: A Review of the Pathogenesis, Evaluation and Treatment
TLDR
A comprehensive review of the literature was performed, and the data were assimilated with evidence from practice and a detailed discussion of the aetiology, pathogenesis, evaluation and management of infraorbital dark circles is provided.
Update in minimally invasive periorbital rejuvenation with a focus on platelet‐rich plasma: A narrative review
The periorbital region is among the first areas to be affected by the process of aging, which is influenced by genetic and constitutional factors. As the region plays an important role in overall…
Koffein - Wirkmechanismen und kosmetische Verwendung
Koffein findet in der Kosmetik zunehmend breite Anwendung, da es hohe biologische Aktivität zeigt und die Hautbarriere zu durchdringen vermag. Das Alkaloid wird häufig als hydrophile Modellsubstanz…
...
1
2
...

References

SHOWING 1-10 OF 15 REFERENCES
Caffeine Topical Gel Formulation
Caffeine was used topically as one of many ingredients in various cosmetic preparations for reducing under-eye puffiness and dark circles. Gels containing 3% w/w caffeine as an active ingredient were…
Topical delivery of caffeine from some commercial formulations.
Skin permeation of propranolol from polymeric film containing terpene enhancers for transdermal use.
Comparison of Cutaneous Bioavailability of Cosmetic Preparations Containing Caffeine or α-Tocopherol Applied on Human Skin Models or Human Skin ex vivo at Finite Doses
TLDR
It was demonstrated that the rank order of solute permeability could be correctly predicted when the preparation was applied at a finite dose in human skin models, at least when solutes with far different physicochemical properties such as caffeine and α-tocopherol were used.
A double-blind evaluation of the activity of an anti-cellulite product containing retinol, caffeine, and ruscogenine by a combination of several non-invasive methods.
TLDR
A double-blind, randomized, placebo-controlled study was conducted with 46 healthy female volunteers in order to test an anti-cellulite product containing retinol, caffeine and ruscogenine and showed its superiority versus the placebo in skin macrorelief and an increase in cutaneous microcirculation.
Investigation of newborn pig skin as an in vitro animal model for transdermal drug delivery
TLDR
Investigation of the suitability of newborn pig skin as a model in percutaneous absorption studies of drugs found it to have a similar permeation properties to human skin, and factor difference values suggest that as a human skin substitute, newborn pigskin may be a suitable model for per cutaneous absorption screening studies.
Dependence of corticosteroid penetration on the vehicle.
The penetration of corticosteroids through epidermal membranes in vitro proved to be better when the corticosteroid was dissolved in, or salicylic acid was added to, the vehicle. Hydrocortisone 17…
Percutaneous absorption of ibuprofen: Vehicle effects on transport through rat skin
Strategies for overcoming the stratum corneum
TLDR
There is a necessity to regulate the intradermal disposition of drugs to develop a more efficient transdermal drug delivery system after overcoming the skin barrier.
Vehicle effect on topical drug delivery. III. Effect of Azone on the cutaneous permeation of metronidazole and propylene glycol
...
1
2
...