Evaluation of CYP2D6 phenotype in the Yoruba Nigerian population.


BACKGROUND There is a lack of information on CYP2D6, a major metabolizing enzyme, in Africa ethnic nationalities. The objective was to determine CYP2D6 phenotype in Yoruba Nigerians using dextromethorphan (DEX). METHOD A total of 89 healthy volunteers received 30 mg of DEX orally followed by blood and urine sample collection at 3-hour and over 8 h post… (More)
DOI: 10.1080/17512433.2017.1362979


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@article{Adedeji2017EvaluationOC, title={Evaluation of CYP2D6 phenotype in the Yoruba Nigerian population.}, author={Waheed Adeola Adedeji and Sharon Iyobor Igbinoba and Titilayo O Fakeye and Ibrahim Adebayo Oladosu and Fatai Adewale Fehintola and Qing Ma and Gene D. Morse}, journal={Expert review of clinical pharmacology}, year={2017}, volume={10 10}, pages={1145-1152} }