Evaluation of CD4+ CD25+ FoxP3+ Regulatory T cells and FoxP3 and CTLA-4 gene Expression in Patients wwith Newly Diagnosed Tuberculosis in Northeast of Iran

@inproceedings{Ghazalsofala2015EvaluationOC,
  title={Evaluation of CD4+ CD25+ FoxP3+ Regulatory T cells and FoxP3 and CTLA-4 gene Expression in Patients wwith Newly Diagnosed Tuberculosis in Northeast of Iran},
  author={Roghayeh Ghazalsofala and Seyed Abdolrahim Rezaee and Houshang Rafatpanah and Rosita Vakili and Kiarash Ghazvini and Fatemeh Heidarnejad and Somaye Sobhani and Narges Valizadeh and Marayam Azami and Marzieh Rahimzadegan and Amir Mohammad Hashem Asnaashari},
  booktitle={Jundishapur journal of microbiology},
  year={2015}
}
BACKGROUND Tuberculosis (TB) is the world's second most common infectious disease after Human Immunodeficiency Virus Infection/Acquired Immunodeficiency Syndrome (HIV/AID) and the most frequent cause of mortality especially in developing countries. T regulatory (Treg) cells, which have suppressive activity and express forkhead winged-helix family transcriptional repressor p3 (FoxP3), suppress the immune responses against pathogens such as Mycobacterium tuberculosis. There are controversial… CONTINUE READING