Corpus ID: 81618675

Evaluation of Anti-Arthritic Activity of The Ethanolic Extract of Mimosa Pudica Linn. in Complete Freund’s Adjuvant Induced Arthritis in Wistar Rats

  title={Evaluation of Anti-Arthritic Activity of The Ethanolic Extract of Mimosa Pudica Linn. in Complete Freund’s Adjuvant Induced Arthritis in Wistar Rats},
  author={K. Kanimozhi},
Rheumatoid arthritis is an inflammatory, autoimmune disorder which destroys it‟s own immune system. The immunologically mediated Complete Freund‟s adjuvant induced arthritic model of chronic inflammation is considered as the best available experimental model of rheumatoid arthritis[70].Complete Freund‟s adjuvant-induced arthritis is a model of chronic polyarthritis with features that resemble rheumatoid arthritis. In Complete freund‟s adjuvant-induced arthritis model, rats developed a… Expand
A Study on Comparative Antioxidant Properties of Mimosa pudica, Vachellia nilotica, Leucas aspera, Phyllanthus niruri, emidesmus indicus and Adhatoda vasica
The roots of this plant are used for the treatment of inflammation, asthma, dysentery, leprosy, burning sensation, piles, jaundice, bilious fevers and tooth ache, skin diseases. Expand


Treatment of Rat Adjuvant Arthritis with Flavonoid (Detralex®), Methotrexate, and Their Combination
Interestingly, the arthritis‐induced decrease of bone mineral density in AA rats was significantly lower only in the group treated with the combination of Detralex and methotrexate, suggesting that this may be related to the beneficial effect of DetRalex on microcirculation, especially on venules and lymphatic vessels. Expand
Adjuvant-induced arthritis in rats. II. Drug effects on physiologic, biochemical and immunologic parameters.
The results suggest that adjuvant arthritis is a sensitive model, with improved specificity, to detect both anti-inflammatory and immunosuppressive agents. Expand
The anti-arthritic activity of stem barks of Alangium salviifolium wang belonging to family Alangiaceae was studied in rats. The barks of Alangium salviifolium wang were collected and dried in shadeExpand
Autopathogenic correlation of periodontitis and rheumatoid arthritis.
The aim of this review is to map the immunological and serological profiles of PO, and to unveil the parameters that connect PO with the appearance of RA at clinical, prognostic and pathogenetic levels. Expand
Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies.
It is proposed that reactive oxygen species set the threshold for T cell activation and thereby regulate chronic autoimmune inflammatory diseases like RA and new possibilities for preventive and therapeutic treatment of chronic inflammatory diseases are discussed. Expand
Autoimmune Mechanisms Involved in the Pathogenesis of Rheumatoid Arthritis
Rheumatoid arthritis patients who belong to subtype HLA DR4, Dw4 (DR B1 or 0401, Dw14 (0404/0408), or Dw15 (0405/0410) are most likely to be seropositive for RF and to have severe progressive disease. Expand
Antiarthritic Evalution of Crateva religiosaExtracts
The alcoholic extracts found to show more effect than aquous extracts in the terms of % of inhibition, and both the alcoholic and aqueous extracts significantly decrease the paw edema on 28th day. Expand
Association between arthritis score at the onset of the disease and long-term locomotor outcome in adjuvant-induced arthritis in rats
Decreased ankle mobility can be considered a driver of locomotion impairment in AIA and had a good prognostic value for long-term locomotor outcome. Expand
Cells of the synovium in rheumatoid arthritis. Macrophages
This paper presents optimization strategies to selectively target macrophages by agents tailored to specific features of macrophage activation, striking the cell population that mediates/amplifies most of the irreversible tissue destruction and sparing other cells that have no (or only marginal) effects on joint damage. Expand
Anti-Citrullinated Protein Antibodies in Rheumatoid Arthritis: As Good as it Gets?
The combined application of anti-CCP2 and anti-MCV assays can improve the laboratory diagnostics of RA and there is an increasing need for developing new diagnostic strategies after careful evaluation of the characteristics of the available assays. Expand