Evaluation of Analgesic, Anticonvulsant and Hypnotic activities of Pyrenacanthia staundtii

@inproceedings{Awe2005EvaluationOA,
  title={Evaluation of Analgesic, Anticonvulsant and Hypnotic activities of Pyrenacanthia staundtii},
  author={Emmanuel Olorunju Awe and J. M. Makinde and O. A. Wahkeel and Adewale Olufunsho Adeloye},
  year={2005}
}
An Aqueous leaf extract of Pyrenacanthia Staundtii (AqPs) was studied for central nervous activities. The extract (100.0 – 400.0 mg/kg i. p). significantly (p<0.05) inhibited acetic-acid induced abdominal constriction, and both the early and or late phases of formalininduced paw licking in mice. AqPs (100-400mg/kg i.p.) also demonstrated a protective effect against strychnine-induced convulsion. The extract potentiated the hypnotic effect of hexobarbitone following i.p. injection at the dose… CONTINUE READING

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