Evaluation of Absorbability of Macromolecular Substances in the Oral Mucosa and Skin using a Three-Dimensional Tissue Culture Model

  title={Evaluation of Absorbability of Macromolecular Substances in the Oral Mucosa and Skin using a Three-Dimensional Tissue Culture Model},
  author={Mariko Takenokuchi and Keiichi Kadoyama and Daisuke Yoshida and Shigeki Takaki and Ryoma Yamamoto and Katsuyasu Saigo and Taizo Taniguchi},
  journal={Biology and medicine},
Introduction: Collagen exists in various connective tissues and helps to provide them mechanical strength and elasticity. The main component of the tendon is properly arranged collagen fibers withstanding very strong forces. The compactly packed collagen fine fibers inside the bone and cartilage increase their elasticity. Collagen also helps skin elasticity and strength. Hyaluronic acid widely exists in extracellular matrix, such as joints and skin. It plays an important role in maintaining… 
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