Evaluation of ADAMTS17 in Chinese Shar-Pei with primary open-angle glaucoma, primary lens luxation, or both.

@article{Oliver2018EvaluationOA,
  title={Evaluation of ADAMTS17 in Chinese Shar-Pei with primary open-angle glaucoma, primary lens luxation, or both.},
  author={James A. C. Oliver and Sophie Rustidge and Louise Pettitt and Christopher A. Jenkins and Fabiana H. G. Farias and Elizabeth A. Giuliano and Cathryn Mellersh},
  journal={American journal of veterinary research},
  year={2018},
  volume={79 1},
  pages={
          98-106
        }
}
OBJECTIVE To evaluate the coding regions of ADAMTS17 for potential mutations in Chinese Shar-Pei with a diagnosis of primary open-angle glaucoma (POAG), primary lens luxation (PLL), or both. ANIMALS 63 Shar-Pei and 96 dogs of other breeds. PROCEDURES ADAMTS17 exon resequencing was performed on buccal mucosal DNA from 10 Shar-Pei with a diagnosis of POAG, PLL, or both (affected dogs). A candidate causal variant sequence was identified, and additional dogs (53 Shar-Pei [11 affected and 42… CONTINUE READING
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