Evaluation of 5-S-cysteinyldopa as a marker of melanoma progression: 10 years' experience.

@article{Wakamatsu2002EvaluationO5,
  title={Evaluation of 5-S-cysteinyldopa as a marker of melanoma progression: 10 years' experience.},
  author={Kazumasa Wakamatsu and Toshiro Kageshita and Masutaka Furue and Naohito Hatta and Yutaka Kiyohara and Juichiro Nakayama and Tomojiro Ono and Toshiaki Saida and Masahiko Takata and Tomohiro Tsuchida and Hisashi Uhara and Akifumi Yamamoto and Naoya Yamazaki and Akiko Naito and Shosuke Ito},
  journal={Melanoma research},
  year={2002},
  volume={12 3},
  pages={245-53}
}
5-S-Cysteinyldopa (5-S-CD) has been used as a biochemical marker of melanoma progression. In this study, we measured serum levels of 5-S-CD in 2648 samples taken from 218 patients in order to evaluate the usefulness of this parameter in following melanoma progression and prognosis. 5-S-CD levels were significantly elevated above the upper limit of the normal range (10 nmol/l) in stage IV melanoma patients. The sensitivity of elevated serum 5-S-CD levels in detecting distant metastasis was 73… CONTINUE READING