Evaluation of 2,5-hexanedione in urine of workers exposed to n-hexane in Brazilian shoe factories.

@article{Santos2002EvaluationO2,
  title={Evaluation of 2,5-hexanedione in urine of workers exposed to n-hexane in Brazilian shoe factories.},
  author={C. R. dos Santos and Miriam Meyer Meyer Passarelli and Elizabeth de Souza Nascimento},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2002},
  volume={778 1-2},
  pages={
          237-44
        }
}
Urinary 2,5-hexanedione (2,5-HD) is used as a biomarker for biological monitoring of workers exposed to n-hexane. The purpose of this study was to compare two types of treatment of urine samples during clean-up (with and without acidic hydrolysis) and to study the exposure situation of workers exposed to n-hexane during shoe manufacturing. There, various glues containing n-hexane are used. Quantification of 2,5-HD was carried out by gas chromatography and flame ionization detection (GC-FID… Expand
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