Evaluation of 188Re-labeled NGR–VEGI protein for radioimaging and radiotherapy in mice bearing human fibrosarcoma HT-1080 xenografts

Abstract

Vascular endothelial growth inhibitor (VEGI) is an anti-angiogenic protein, which includes three isoforms: VEGI-174, VEGI-192, and VEGI-251. The NGR (asparagine–glycine–arginine)-containing peptides can specifically bind to CD13 (Aminopeptidase N) receptor which is overexpressed in angiogenic blood vessels and tumor cells. In this study, a novel NGR–VEGI… (More)
DOI: 10.1007/s13277-016-4810-y

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Cite this paper

@article{Ma2016EvaluationO1, title={Evaluation of 188Re-labeled NGR–VEGI protein for radioimaging and radiotherapy in mice bearing human fibrosarcoma HT-1080 xenografts}, author={Wenhui Ma and Yahui Shao and Weidong Yang and Guiyu Li and Yuan-qiang Zhang and Mingru Zhang and Changjing Zuo and Kai Chen and Jing Wang}, journal={Tumor Biology}, year={2016}, volume={37}, pages={9121-9129} }