Evaluation of [¹⁸F]PFH PET renography to predict future disease progression in a rat model of autosomal dominant polycystic kidney disease.

@article{Pathuri2016EvaluationO,
  title={Evaluation of [¹⁸F]PFH PET renography to predict future disease progression in a rat model of autosomal dominant polycystic kidney disease.},
  author={Gopal Pathuri and Andria F. Hedrick and Vibhudutta Awasthi and Benjamin Cowley and Hariprasad Gali},
  journal={Nuclear medicine and biology},
  year={2016},
  volume={43 1},
  pages={1-5}
}
INTRODUCTION Prognostic markers for progression of polycystic kidney disease (PKD) are limited. We evaluated the potential of early para-[(18)F]fluorohippurate ([(18)F]PFH) positron emission tomography (PET) renography to predict future progression of PKD in Han:SPRD rats with slowly progressive autosomal dominant PKD. MATERIALS AND METHODS Male and female heterozygous (Cy/+) and normal littermate (+/+) Han:SPRD rats underwent [(18)F]PFH PET renography and blood sampling to measure serum… CONTINUE READING