Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer.

@article{Jenkinson2015EvaluationIP,
  title={Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer.},
  author={Claire Jenkinson and Vanessa Elliott and Usha Menon and Sophia Apostolidou and O E Fourkala and Aleksandra Gentry-Maharaj and Stephen P. Pereira and Ian Jacobs and Trevor F. Cox and William Greenhalf and John F Timms and Robert Sutton and John P Neoptolemos and Eithne M Costello},
  journal={Journal of proteomics},
  year={2015},
  volume={113},
  pages={400-2}
}
UNLABELLED Circulating intercellular adhesion molecule-1 (ICAM-1) and tissue inhibitor of metalloproteinases-1 (TIMP-1) have been widely proposed as potential diagnostic biomarkers for pancreatic ductal adenocarcinoma (PDAC). We report on serum protein levels prior to clinical presentation of pancreatic cancer. Serum ICAM-1 and TIMP-1 were measured by ELISA in two case–control sets: 1) samples from patients diagnosed with pancreatic cancer (n = 40), chronic pancreatitis (n = 20), benign… CONTINUE READING
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Serum biomarker panels for the detection of pancreatic cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2011

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