Evaluation for antioxidant and renoprotective activity of olmesartan using nephrectomy rats.

@article{Kadowaki2009EvaluationFA,
  title={Evaluation for antioxidant and renoprotective activity of olmesartan using nephrectomy rats.},
  author={Daisuke Kadowaki and Makoto Anraku and Yuka Tasaki and Kazuaki Taguchi and Kazuki Shimoishi and Hakaru Seo and Sumio Hirata and Toru Maruyama and Masaki Otagiri},
  journal={Biological & pharmaceutical bulletin},
  year={2009},
  volume={32 12},
  pages={2041-5}
}
Angiotensin II type 1 receptor blockers, which inhibit the rennin-angiotensin system, are used in the treatment of hypertension. In addition to their ability to lower blood pressure, these compounds have also been reported to protect organs, such as kidney and heart. Although the mechanisms of these protective effects are not fully understood, it is generally thought that their antioxidant effects likely play a role. The aim of the present study was to characterize the relationship between the… CONTINUE READING

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