Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.
@article{Cals2008EvaluationAI, title={Evaluation and improvement of a reliable diagnosis of cirrhosis by blood tests.}, author={P. Cal{\`e}s and J. Boursier and V. de L{\'e}dinghen and P. Halfon and Y. Bacq and V. Leroy and N. Dib and F. Oberti and A. Sawadogo and M-C Rousselet and F. Lunel}, journal={Gastroenterologie clinique et biologique}, year={2008}, volume={32 12}, pages={ 1050-60 } }
OBJECTIVE
To evaluate the rates of reliable diagnosis of cirrhosis by two usual blood tests.
METHODS
Reliable diagnosis was mainly evaluated by comparing rates of positive (PPV) and negative (NPV) predictive values with FibroTest and FibroMeters, as either standard test or specifically designed for cirrhosis, in 1056 patients with chronic hepatitis C.
RESULTS
Using the diagnostic limits provided by fibrosis stage scales, the PPV for cirrhosis was: standard FibroMeters: 68.5% versus… CONTINUE READING
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References
SHOWING 1-10 OF 22 REFERENCES
Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C
- Medicine
- European journal of gastroenterology & hepatology
- 2009
- 66
Prospective comparison of six non-invasive scores for the diagnosis of liver fibrosis in chronic hepatitis C.
- Medicine
- Journal of hepatology
- 2007
- 235
Diagnostic accuracy, reproducibility and robustness of fibrosis blood tests in chronic hepatitis C: a meta-analysis with individual data.
- Medicine
- Clinical biochemistry
- 2008
- 72
Accuracy of liver stiffness measurement for the diagnosis of cirrhosis in patients with chronic liver diseases
- Medicine
- Hepatology
- 2006
- 473
Stepwise combination algorithms of non-invasive markers to diagnose significant fibrosis in chronic hepatitis C.
- Medicine
- Journal of hepatology
- 2006
- 273
Diagnosis of cirrhosis by transient elastography (FibroScan): a prospective study
- Medicine
- Gut
- 2006
- 1,109
- PDF
Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV FibroSure) and necrosis (ActiTest) in patients with chronic hepatitis C
- Medicine
- Comparative hepatology
- 2004
- 360
- PDF
Comparison of test performance profile for blood tests of liver fibrosis in chronic hepatitis C.
- Medicine
- Journal of hepatology
- 2007
- 139
Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C.
- Medicine
- Clinical chemistry
- 2004
- 321
- PDF