Evaluation and comparison of various separation techniques for the analysis of closely-related compounds of pharmaceutical interest.


The aim of the present work was to compare various separation techniques for the fast analysis of closely-related compounds, including structurally-related compounds, positional isomers, diastereoisomers, Z/E isomers. Three analytical techniques were evaluated, namely ultra high performance liquid chromatography (UHPLC), ultra high performance supercritical… (More)
DOI: 10.1016/j.chroma.2013.01.095


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