Evaluating the role of flupirtine for postcraniotomy pain and compare it with diclofenac sodium: a prospective, randomized, double blind, placebo-controlled study.

@article{Yadav2014EvaluatingTR,
  title={Evaluating the role of flupirtine for postcraniotomy pain and compare it with diclofenac sodium: a prospective, randomized, double blind, placebo-controlled study.},
  author={G. Sreenivasa Yadav and Sujali Choupoo and Saurabh Kumar Das and Susanta Kumar Das and Shailaja Shankar Behera and Sandeep Khuba and Lal Dhar Mishra and Dinesh Kumar Singh},
  journal={Journal of neurosurgical anesthesiology},
  year={2014},
  volume={26 1},
  pages={32-6}
}
BACKGROUND Patients undergoing craniotomy, experience moderate to severe pain in postoperative period. Flupirtine does not have side effects like sedation and increase postoperative bleeding, so it may be a useful analgesic in neurosurgical patients. We designed this prospective, randomized, double blind, placebo-controlled study to evaluate the role of flupirtine for postcraniotomy pain and compare it with diclofenac sodium. MATERIALS AND METHODS A total of 390 adults (18 to 70 y), American… CONTINUE READING