Evaluating the efficacy of amikacin in low-clearance unilamellar liposomes in a s. Aureus local infection model.

Abstract

Traditional therapies for Staphylococcal infections such as osteomyelitis or localized abscesses have a difficult time penetrating into tissue sites. To effectively ameliorate these infections, prolonged therapy and/or high doses of antibiotics are frequently required. Aminoglycosides, such as amikacin, are not routinely utilized for treating local… (More)
DOI: 10.1081/LPR-100108465

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