Evaluating the efficacy and safety of antidepressants in patients with bipolar disorder

  title={Evaluating the efficacy and safety of antidepressants in patients with bipolar disorder},
  author={E. Cheniaux and A. Nardi},
  journal={Expert Opinion on Drug Safety},
  pages={893 - 913}
  • E. Cheniaux, A. Nardi
  • Published 2019
  • Medicine
  • Expert Opinion on Drug Safety
  • ABSTRACT Introduction: The use of antidepressants (AD) in the treatment of bipolar depression is one of the most controversial issues in psychopharmacology. For some, AD are useful, but, for others, they should never be used in bipolar depression. Areas covered: This review examines published clinical studies on the use of ADs in bipolar depression, addressing their clinical efficacy and the occurrence of side effects, manic switches, cycle acceleration, and suicidal behavior. Meta-analyzes and… CONTINUE READING

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