Evaluating the consistency of differential expression of microRNA detected in human cancers.

@article{Gong2011EvaluatingTC,
  title={Evaluating the consistency of differential expression of microRNA detected in human cancers.},
  author={Xue Gong and Ruihong Wu and Hongwei Wang and Xinwu Guo and Dong Wang and Yunyan Gu and Yuannv Zhang and Wenyuan Zhao and Lixin Cheng and Chenguang Wang and Zheng Guo},
  journal={Molecular cancer therapeutics},
  year={2011},
  volume={10 5},
  pages={
          752-60
        }
}
Differential expression of microRNA (miRNA) is involved in many human diseases and could potentially be used as a biomarker for disease diagnosis, prognosis, and therapy. However, inconsistency has often been found among differentially expressed miRNAs identified in various studies when using miRNA arrays for a particular disease such as a cancer. Before broadly applying miRNA arrays in a clinical setting, it is critical to evaluate inconsistent discoveries in a rational way. Thus, using data… CONTINUE READING

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